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The goal of the research is to help develop Pharm kinetic models by studying the interactions within the cytochrome p450 metabolon. P450 Is a large variety of enzymes that stimulate oxidation in organic matter. The substrates of cytochrome P 450 proteins include intermediary metabolisms such as fat, cortisone, hormones, and psychic chemicals, such as sedative drugs and other toxic substances. Cytochrome P 450 is the primary enzyme involved in metabolism and metabolism. The cytochrome P450 is a family of monooxygenases. These enzymes are found in most sorts of life. It’s critical in many vital paths. Specifically, they are responsible for ~ 70% of all drug metabolism in humans. P450 is of great interest since it was first identified in 1962

In particular, we are studying the binding of time-dependent inhibitors to the active site of cytochrome P450s by looking at changes in the native luminescence of those proteins

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